Pheochromocytoma is a rare but serious tumor of the adrenal gland that leads to the excessive production of catecholamines—hormones like adrenaline and noradrenaline. This results in sudden spikes in blood pressure, rapid heart rate, excessive sweating, and severe headaches. Although usually benign, pheochromocytomas can cause life-threatening complications if left untreated. Under the expert care of Dr. Pruthvi Raj Honnaiah, patients receive precise diagnosis and advanced treatment for this adrenal disorder.

Causes & Risk Factors

Pheochromocytomas originate from the adrenal medulla, the inner part of the adrenal glands. While most cases are sporadic, some are linked to genetic conditions, including:

• Multiple Endocrine Neoplasia Type 2 (MEN 2)
• Von Hippel-Lindau Syndrome (VHL)
• Neurofibromatosis Type 1 (NF1)
• Paragangliomas (extra-adrenal tumors related to pheochromocytoma)

Symptoms of Pheochromocytoma

Patients with pheochromocytoma often experience sudden, episodic symptoms due to excessive hormone secretion, including:

• Severe high blood pressure (hypertension), resistant to medications
• Intense headaches
• Excessive sweating (diaphoresis)
• Rapid or irregular heartbeat (palpitations)
• Anxiety, panic attacks, or tremors
• Flushing or pale skin
• Unexplained weight loss
• High blood sugar levels

These symptoms often come in bursts and may be triggered by stress, exercise, surgery, or certain foods (e.g., tyramine-rich foods like aged cheese or red wine).

Diagnosis of Pheochromocytoma

At Dr. Pruthvi Raj’s clinic, a thorough diagnostic approach ensures early detection and effective management:

Blood & Urine Tests:

• Plasma Free Metanephrines & 24-Hour Urinary Metanephrines – To measure excess catecholamine metabolites.
• Chromogranin A Levels – A tumor marker.

Imaging Studies:

• CT or MRI of the Adrenal Glands – To locate the tumor.
• MIBG Scan (Metaiodobenzylguanidine Scintigraphy) – For detecting extra-adrenal tumors (paragangliomas).
• Genetic Testing – If a hereditary condition is suspected.

Treatment Options

The primary treatment for pheochromocytoma is surgical removal (adrenalectomy). However, pre-surgical management is crucial to prevent severe complications during surgery.

Pre-Surgery Preparation:

• Alpha-Blockers (e.g., Phenoxybenzamine, Prazosin) – To control blood pressure.
• Beta-Blockers (e.g., Propranolol) – After alpha-blockade to manage heart rate.
• High-Sodium Diet & Hydration – To stabilize blood volume before surgery.

Surgical Treatment:

• Minimally Invasive Laparoscopic Adrenalectomy – The preferred approach for tumor removal, reducing recovery time and complications.
• Open Surgery – May be required for larger or malignant tumors.

Post-Surgery Care & Follow-Up:

• Regular monitoring – For blood pressure stability and hormone levels.
• Lifelong follow-up – If a genetic condition is present.

Why Choose Dr. Pruthvi Raj for Pheochromocytoma Treatment?

With expertise in adrenal disorders, minimally invasive adrenal surgery, and laparoscopic techniques, Dr. Pruthvi Raj Honnaiah ensures precise diagnosis, safe surgical management, and long-term follow-up for pheochromocytoma patients. His patient-focused approach minimizes risks and optimizes recovery.