Conn’s Syndrome: Understanding Primary Aldosteronism
Conn’s syndrome, also known as primary aldosteronism, is a condition where the adrenal glands produce excess aldosterone, a hormone responsible for regulating blood pressure and electrolyte balance. Overproduction of aldosterone leads to high blood pressure (hypertension) and low potassium levels (hypokalemia), increasing the risk of cardiovascular complications. Under the expert care of Dr. Pruthvi Raj Honnaiah, patients receive comprehensive evaluation, precise diagnosis, and tailored treatment to manage Conn’s syndrome effectively.
Causes of Conn’s Syndrome
The overproduction of aldosterone in Conn’s syndrome is usually caused by:
- Adrenal Adenoma (Aldosterone-Producing Tumor): A benign tumor in one adrenal gland that leads to excessive aldosterone secretion.
- Bilateral Adrenal Hyperplasia: Overactivity of both adrenal glands, causing increased aldosterone production.
- Genetic Factors: In rare cases, familial hyperaldosteronism can lead to excessive aldosterone levels.
Symptoms of Conn’s Syndrome
Many patients with Conn’s syndrome experience persistent high blood pressure, which may not respond well to standard medications. Other symptoms include:
- Severe or resistant hypertension
- Frequent muscle cramps, weakness, or fatigue due to potassium imbalance
- Excessive thirst and frequent urination (polydipsia and polyuria)
- Tingling sensations or numbness (paresthesia)
- Headaches and blurred vision due to uncontrolled hypertension
Diagnosis of Conn’s Syndrome
At Dr. Pruthvi Raj’s clinic, diagnosing Conn’s syndrome involves a series of advanced tests, including:
- Blood Tests:
- Aldosterone-to-Renin Ratio (ARR) – A key test to detect excess aldosterone production.
- Electrolyte Panel – To assess potassium and sodium imbalances.
- Imaging Studies:
- CT or MRI Scan – To detect adrenal tumors or hyperplasia.
- Adrenal Vein Sampling (AVS) – A specialized test to determine if the excess aldosterone is coming from one or both adrenal glands.
Treatment Options
The treatment approach depends on the underlying cause of Conn’s syndrome:
For Adrenal Tumors (Adenomas):
- Minimally Invasive Adrenalectomy – Surgical removal of the affected adrenal gland, often leading to a cure.
For Bilateral Adrenal Hyperplasia:
- Medication Therapy:
- Aldosterone Antagonists (e.g., Spironolactone, Eplerenone) to block aldosterone effects.
- Blood Pressure Management: Personalized treatment for hypertension.
- Lifestyle Modifications:
- Reducing sodium intake to control blood pressure.
- Potassium-rich diet to balance electrolytes.
- Regular monitoring to prevent complications.
Why Choose Dr. Pruthvi Raj for Conn’s Syndrome Management?
With expertise in adrenal disorders, endourology, and minimally invasive surgery, Dr. Pruthvi Raj Honnaiah provides precise diagnosis and targeted treatment for Conn’s syndrome. His patient-focused approach ensures effective blood pressure control, electrolyte balance, and long-term health improvement.
For expert evaluation and personalized treatment, consult Dr. Pruthvi Raj Honnaiah today.